Diphantoine is an anti-epileptic drug, also called an anticonvulsant. It works by slowing down impulses in the brain that cause seizures.
Diphantoine is used to control seizures. Diphantoine does not treat all types of seizures, and your doctor will determine if it is the right medicine for you.
Diphantoine may also be used for purposes not listed in Diphantoine guide.
How is it given?
1 g orally divided in 3 doses (400 mg, 300 mg, 300 mg) given at 2 hour intervals. Then normal maintenance dosage started 24 hours after loading dose.
Initial dose: 100 mg extended release orally 3 times a day.
Maintenance dose: 100 mg orally 3 to 4 times a day. If seizure control is established with divided doses of three 100 mg capsules daily, once-a-day dosage with 300 mg of extended release Diphantoine sodium may be considered. Alternatively, the dosage may need to be increased up to 200 mg orally 3 times a day, if necessary.
What are the common side effects?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. You may be more likely to have an allergic reaction if you are African-American.
Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive, more depressed, or have thoughts about suicide or hurting yourself.
Call your doctor at once if you have:
fever, swollen glands, sore throat, trouble breathing, painful mouth sores, sores around your eyes;skin rash, easy bruising or bleeding, severe weakness;
severe muscle pain;nausea, vomiting, upper stomach pain, loss of appetite, dark urine, jaundice (yellowing of the skin or eyes);bone pain (especially in your hips, legs, or lower back), trouble with walking; or severe skin reaction–fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.